FORMULATION AND STABILITY STUDY OF BLACK CUMIN (NIGELLA SATIVA L.) SEED OIL EMULSION USING SUCROSE PALMITATE AS EMULSIFIER
نویسندگان
چکیده
Objective: An emulsion of black cumin seed oil was developed using an orally safe surfactant, sucrose palmitate, to make it more comfortable consume. Methods: The made a 3% concentration palmitate emulsify 5% (F1) and 7.5% (F2) the stable emulsion. hedonic test applied 30 panelists, showing accepted formulation. Results: pH value each formulation degraded during 12 w storage. formula has better physical stability, its bioactive component, Thymoquinone, showed slight degradation on first day. But rapid after 60 d storage due instability in solution. F1 (mean = 3.1667) is preferred than F2 3) 1-5 scale, with significance score (p) valued less 0.05 considered be significantly different from original form. Conclusion: can
منابع مشابه
Deodorizing Substance in Black Cumin (Nigella sativa L.) Seed Oil.
A deodorizing substance in black cumin (Nigella sativa L.), a spice for curry and vegetable foods in Southwest Asia, was examined. The essential oil prepared from the seeds of this plant exhibited strong deodorizing activity against methyl mercaptan, which is a main factor in oral malodor. After purification with silica gel column chromatography, the active substance in black cumin seed oil was...
متن کاملResponse of Seed Yield and Essential oil of Black Cumin (Nigella sativa L.) Affected as Foliar Spraying of Nano-fertilizers
In order to investigate the effect of micronutrients foliar application on seed yield and essential oil of black cumin, a field experiment was conducted based on Randomized Complete Block Design (RCBD) with three replications at the farmlocated in Naqadeh city, West Azerbaijan province, Iran, during 2015-2016 growing season. Treatments were separate application of Nano-Iron, Nano-Zinc and Nano-...
متن کاملAnticancer activities of Nigella sativa (black cumin).
Nigella sativa has been used as traditional medicine for centuries. The crude oil and thymoquinone (TQ) extracted from its seeds and oil are effective against many diseases like cancer, cardiovascular complications, diabetes, asthma, kidney disease etc. It is effective against cancer in blood system, lung, kidney, liver, prostate, breast, cervix, skin with much safety. The molecular mechanisms ...
متن کاملScolicidal Effects of Black Cumin Seed (Nigella sativa) Essential Oil on Hydatid Cysts
Surgery remains the preferred treatment for hydatid cyst (cystic echinococcosis, CE). Various scolicidal agents have been used for inactivation of protoscolices during surgery, but most of them are associated with adverse side effects. The present study aimed to evaluate the in vitro scolicidal effect of Nigella sativa (Ranunculaceae) essential oil and also its active principle, thymoquinone, a...
متن کاملNigella sativa (Black Cumin) Seed Extract Alleviates Symptoms of Allergic Diarrhea in Mice, Involving Opioid Receptors
The incidence of food hypersensitivity and food allergies is on the rise and new treatment approaches are needed. We investigated whether N. sativa, one of its components, thymoquinone, or synthetic opioid receptor (OR)-agonists can alleviate food allergy. Hence, ovalbumin (OVA)-sensitized BALB/c-mice were pre-treated either with a hexanic N. sativa seed extract, thymoquinone, kappa-(U50'4889) ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Applied Pharmaceutics
سال: 2022
ISSN: ['0975-7058']
DOI: https://doi.org/10.22159/ijap.2022v14i5.44945